What Is Dual Marker Test?

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Written By Charlotte Miller

Are you curious to know what is dual marker test? You have come to the right place as I am going to tell you everything about dual marker test in a very simple explanation. Without further discussion let’s begin to know what is dual marker test?

In the realm of prenatal screening, the Dual Marker Test emerges as a crucial diagnostic tool providing valuable insights into the health and development of the fetus. This article aims to offer a detailed and knowledgeable exploration of what the Dual Marker Test is, its significance during pregnancy, the testing process, and the interpretation of results.

What Is Dual Marker Test?

The Dual Marker Test, also known as the Double Marker Test, is a prenatal screening procedure designed to assess the risk of chromosomal abnormalities, particularly Down syndrome (Trisomy 21) and Edwards syndrome (Trisomy 18), in the developing fetus. This non-invasive test involves analyzing specific markers in the maternal blood to estimate the likelihood of genetic anomalies.

Dual Marker Test In Pregnancy:

Administered during the first trimester of pregnancy, typically between 11 to 14 weeks, the Dual Marker Test provides expectant parents with essential information about the fetal health. This early screening allows for timely interventions and informed decision-making based on the risk assessment.

How Dual Marker Test Is Done:

The Dual Marker Test is a relatively straightforward procedure that involves:

  • Blood Sample Collection: A small sample of the mother’s blood is drawn.
  • Analysis of Markers: The blood sample is then analyzed for specific markers, including human chorionic gonadotropin (hCG) and pregnancy-associated plasma protein-A (PAPP-A).
  • Risk Assessment: The results are used to assess the risk of chromosomal abnormalities in the fetus.

Double Marker Test Negative Means:

A negative result from the Dual Marker Test implies a lower likelihood of chromosomal abnormalities in the fetus. However, it’s important to note that the test is a screening tool, and a negative result does not guarantee the absence of abnormalities. Further diagnostic tests may be recommended for confirmation.

Double Marker Test Normal Values:

Normal values for the Dual Marker Test are determined by assessing the levels of hCG and PAPP-A in the maternal blood sample. These normal values serve as a reference point for calculating the risk of chromosomal abnormalities, with deviations indicating potential concerns.

Double Marker Test Report:

The Dual Marker Test report typically includes information on the levels of hCG and PAPP-A, along with the calculated risk for Down syndrome and Edwards syndrome. The report aids healthcare providers and expectant parents in making informed decisions regarding additional diagnostic tests or interventions.

Quadruple Marker Test:

Building upon the Dual Marker Test, the Quadruple Marker Test includes additional markers such as inhibin A, providing a more comprehensive assessment of the risk of chromosomal abnormalities. This test is often recommended for a more detailed evaluation during the second trimester.

Double Marker Test Price:

The cost of the Dual Marker Test may vary based on factors such as geographic location, healthcare facility, and additional services included in the screening package. It’s advisable for expectant parents to inquire about the test price and coverage before undergoing the procedure.


The Dual Marker Test plays a pivotal role in prenatal care, offering valuable insights into the potential risk of chromosomal abnormalities. As an informative and non-invasive screening tool, it empowers expectant parents to make informed decisions about their pregnancy journey.


What Is Done In Dual Marker Test?

A blood sample and an ultra-sound examination constitute a double marker test. The free beta hCG (human chorionic gonadotropin) and PAPP-A are the two markers analysed in the double marker test (pregnancy-associated plasma protein A). The placenta secretes a glycoprotein hormone called free beta-hCG in pregnant women.

Does Double Marker Test Reveal Gender?

Does a double marker test reveal the gender? No, it is not possible to predict the gender of the foetus with a double marker test. This is because this blood test is conducted between the 8th and 14th weeks of gestation for determining chromosomal abnormalities.

What Is The Difference Between Nt Scan And Double Marker Test?

While the NT scan is an ultrasound test, the double marker test is a blood test. Apart from the method, there are no significant differences between the two tests.

What Is Included In Double Marker Test In Pregnancy?

The Double Marker Test, as the name suggests, measures only two markers in the mother’s blood: hCG and pregnancy-associated plasma protein-A (PAPP-A). The test is typically performed during the first trimester of pregnancy and is used to assess the risk of chromosomal abnormalities in the fetus.

I Have Covered All The Following Queries And Topics In The Above Article

Double Marker Test Price

Double Marker Test Normal Report Images

Dual Marker Test In Pregnancy

Double Marker Test Negative Means

How Double Marker Test Is Done

Double Marker Test Normal Values

Double Marker Test Report

Quadruple Marker Test

What Is Dual Marker Test